Comparing R-454B R-410 and R-22: What You Need to Know About Refrigerant Options
- Johnny

- Jan 20
- 3 min read
Choosing the right refrigerant is crucial for HVAC systems, impacting performance, environmental footprint, and regulatory compliance. As the industry moves toward greener solutions, understanding the differences between refrigerants like R-454B, R-410, and R-22 helps professionals and consumers make informed decisions. This post explores these three refrigerants, their applications, benefits, and environmental effects, with practical insights to guide your next HVAC project.

What Is R-454B and Where Is It Used?
R-454B is a newer refrigerant designed as a low global warming potential (GWP) alternative to R-410A. It belongs to the family of hydrofluoroolefins (HFOs), which offer improved environmental performance without sacrificing efficiency or safety.
Applications of R-454B
Residential and commercial air conditioning systems
Heat pumps
Light commercial refrigeration
New HVAC equipment designed for low-GWP refrigerants
R-454B is gaining traction because it can replace R-410A in many systems with minimal modifications. It operates at similar pressures and temperatures, making it a practical choice for manufacturers and service technicians transitioning to greener refrigerants.
Advantages of R-454B
R-454B offers several benefits that make it attractive for modern HVAC needs:
Lower Global Warming Potential
R-454B has a GWP of about 466, which is roughly 78% lower than R-410A’s GWP of 2088. This significant reduction helps meet stricter environmental regulations and supports sustainability goals.
Energy Efficiency
Systems using R-454B often maintain or improve energy efficiency compared to R-410A. This means lower electricity bills and reduced carbon emissions over the system’s lifetime.
Compatibility
Because R-454B operates at pressures close to R-410A, it can be used in existing equipment designs with minor adjustments. This reduces the cost and complexity of switching refrigerants.
Safety
R-454B is mildly flammable (classified as A2L), requiring proper handling but offering a good balance between safety and environmental benefits.
Legacy Refrigerants: R-410 and R-22 in Use Today
While R-454B is emerging as a preferred option, many HVAC systems still rely on older refrigerants like R-410 and R-22.
R-410
R-410 (often referred to as R-410A) has been the industry standard for new air conditioning systems for over a decade. It replaced R-22 because it does not deplete the ozone layer. However, its high GWP has led to regulatory pressure to phase it down.
Environmental Impact
R-410A has zero ozone depletion potential but a high GWP of 2088, contributing significantly to climate change if leaked.
Use Cases
Most residential and commercial AC units installed in the last 10-15 years use R-410A.
Phase-Down
Many countries are reducing R-410A production and encouraging alternatives like R-454B.
R-22
R-22 was the dominant refrigerant for decades but is now being phased out globally due to its ozone depletion potential.
Environmental Impact
R-22 has a high ozone depletion potential and a GWP of about 1810, making it harmful to the environment.
Legacy Systems
Many older HVAC units still use R-22, especially in existing buildings. Servicing these systems requires careful handling and often involves using reclaimed or recycled refrigerant.
Regulatory Status
Production and import of R-22 have been largely banned in many regions, but existing stock and reclaimed supplies remain available for servicing legacy equipment.
Where to Find These Refrigerants
All three refrigerants—R-454B, R-410, and R-22—are available from Haltron.com. Whether you need a low-GWP solution for new installations or supplies for servicing older systems, Haltron.com offers a reliable source for quality refrigerants.
Choosing the Right Refrigerant for Your HVAC Needs
Selecting between R-454B, R-410, and R-22 depends on several factors:
System Age and Compatibility
New systems designed for low-GWP refrigerants benefit from R-454B. Existing R-410A systems may be retrofitted or replaced depending on regulations and performance goals. R-22 systems often require servicing with reclaimed refrigerant or system replacement.
Environmental Regulations
Regions with strict environmental laws favor refrigerants with low GWP and zero ozone depletion potential, making R-454B a forward-looking choice.
Safety Considerations
Mild flammability of R-454B requires trained technicians and proper safety measures. R-410A and R-22 are non-flammable but have other environmental drawbacks.
Cost and Availability
R-454B may have a higher upfront cost but can save money over time through energy efficiency and regulatory compliance. R-22 is becoming scarce and expensive due to phase-out.
Practical Example: Transitioning to R-454B
A commercial building with aging R-410A units plans to upgrade its HVAC system. Choosing R-454B allows the building owner to:
Reduce carbon footprint significantly
Maintain similar system performance
Comply with upcoming regulations limiting high-GWP refrigerants
Benefit from potential energy savings
The transition involves working with HVAC professionals trained in handling A2L refrigerants and ensuring equipment compatibility.
Understanding refrigerant options is essential for making smart HVAC decisions that balance performance, cost, and environmental impact. R-454B represents a promising step toward greener cooling, while R-410 and R-22 continue to serve legacy needs with important considerations.



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